Title: Prevalence of Serum Vitamin B12 Levels among Patients Presented to Hebron Charitable Medical Center, Palestine
Author(s) - Nawaf RN Amro1, Abbas Masalma*2
DOI: - 10.23958/ijirms/vol02-i11/18
B.Sc. Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Arab American University - Jenin, Palestine
M.Sc. Department of Biochemistry and Molecular Biology, Faculty of Medicine, Al-Quds University, East Jerusalem, Palestine.
Background: Vitamin B12 is an essential element for proteins, phospholipids metabolism and neurotransmitters synthesis. It also plays a key role in DNA biosynthesis and cellular energy production. However, vitamin B12 deficiency leads to neurologic and psychiatric disturbances including depression, dementia, and a demyelinating myelopathy. Moreover, it’s also associated with other diseases such as pernicious anemia and other hematologic manifestation. Methods: After approval from Hebron Charitable Medical Center (HCMC), a retrospective study was carried out among patients at Charitable Medical Center (HCMC) in Hebron, Palestine. It was carried out over a period of one year and half starting from January 2013 till June 2014. Aim: This study was conducted to determine the prevalence of vitamin B12 among the patients of HCMC. Results: In general, a total of 305 patients screened for serum vitamin B12 levels were enrolled. There were 90 (29.5%) men and 215 (70.5%) women, there were 285 (93.4%) <60 years old and 20 (6.6%) >60 years old .There were 50 patients (16.4%) had vitamin B12 deficiency. Mean ± SEM levels of B12 in 305 subjects were observed to be 389.73.1±12.93 (range: 60 - 1432 pg/ml). Men had mean value of 423.11±30.17 (range: 60 - 1432 pg/ml) and women had 375.75±13.24 (range: 76 - 1292 pg/ml). Conclusion: This study had highlighted a number of patients that reveals Vitamin B12 deficiency according to gender and age. We recommend the necessary implementation of Vitamin B12 supplements for all men and women with any age.
Keywords: Vitamin B12, Deficiency, Gender, Age.
How to Cite this Article?
"Nawaf RN Amro, Abbas Masalma*" ‘‘Prevalence of Serum Vitamin B12 Levels among Patients Presented to Hebron Charitable Medical Center, Palestine" International Journal of Innovative Research in Medical Science(IJIRMS), http://ijirms.in/index.php, Volume 2 Issue 11, November 2017, p. No. 1546-1549