Abstract

Background: Negative symptoms of schizophrenia have been demonstrated to be due to decreased dopamine in the mesocortical pathways. Stimulant medications are a class of medications that can increase dopamine activity in the mesocortical pathway. Case Presentation: We present the case of a patient whose negative symptoms improved from a Positive and Negative Syndrome (PANSS) score of 39 to 11 on the negative symptoms subscale during a three-week trial of dopamine agonist augmentation of antipsychotic therapy. The score on the positive symptoms subscale on PANSS remained low with a two-point reduction at the end of the three-week period. Conclusion: The potential benefits of using stimulant medications in treating negative symptoms of schizophrenia are discussed.

Keywords: Schizophrenia, Negative Symptoms, Atypical Antipsychotics

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How to Cite
Azizi, H., Zeng, Y. H., Kallikkadan, J., Kahn, A., Olayinka, O., Popoola, O., … Jolayemi, A. (2018). The Use of Stimulant Augmentation of Second Generation Antipsychotics in the Management of Negative Symptoms of Schizophrenia: A Case Report. International Journal of Innovative Research in Medical Science, 3(08), 2163 to 2165. https://doi.org/10.23958/ijirms/vol03-i08/08

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Copyright © 2018 Heela Azizi Yu Hao Zeng Jisha Kallikkadan Alexa Kahn Olaniyi Olayinka Olusegun Popoola Tasmia Khan Dina Rimawi Ali Malik Shantale Williams Sherina Langdon Chidubem Matthew Obegolu Deepa Nuthalapati Rana Alzear Hashem Kalbouneh Ayesha Mahbub Chiedozie Ojimba Ayotomide Oyelakin Kodjovi Kodjo Ahmed Ferdous Saad Oluwole Jegede Ayodeji Jolayemi this is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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This work is licensed under a Creative Commons Attribution 4.0 International License.