Human Coronaviruses: Genetics, Virulence Factors and Pathophysiology, Diseases’ Epidemiology

Gnatoulma Katawa; Banfitebiyi Gambogou; Christèle T. Nguepou; Essoham Ataba; Manuel Ritter; Eya H. Kamassa; Fagdéba D. Bara; Simplice D. Karou; Yaovi Ameyapoh

doi:10.23958/ijirms/vol06-i10/1232

Open Access Publication ISSN: 2455-8737 |

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Review Article | Open Access

Vol. 6 No. 10 (2021) | Page No.: 698 - 712 | https://doi.org/10.23958/ijirms/vol06-i10/1232

Human Coronaviruses: Genetics, Virulence Factors and Pathophysiology, Diseases’ Epidemiology

Gnatoulma Katawa⁺⁻
Banfitebiyi Gambogou⁺⁻
Christèle T. Nguepou⁺⁻
Essoham Ataba⁺⁻
Manuel Ritter⁺⁻
Eya H. Kamassa⁺⁻
Fagdéba D. Bara⁺⁻
Simplice D. Karou⁺⁻
Yaovi Ameyapoh⁺⁻

Advanced School of Biological and Food Techniques (ESTBA) / Laboratory of Microbiology and Food Quality Control / Research Unit in Immunology and Immunomodulation (UR2IM), University of Lomé, Togo

1Advanced School of Biological and Food Techniques (ESTBA) / Laboratory of Microbiology and Food Quality Control / Research Unit in Immunology and Immunomodulation (UR2IM), University of Lomé, Togo. 2Togolese Institute for Agronomic Research (ITRA), Togo

Advanced School of Biological and Food Techniques (ESTBA) / Laboratory of Microbiology and Food Quality Control / Research Unit in Immunology and Immunomodulation (UR2IM), University of Lomé, Togo

Institute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany

Advanced School of Biological and Food Techniques (ESTBA) / Laboratory of Microbiology and Food Quality Control / Research Unit in Immunology and Immunomodulation (UR2IM), University of Lomé, Togo

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Published: 2021-10-08

Abstract

Coronaviruses are pathogens for both animals and humans. The recent Coronavirus Disease (Covid-19), caused by a novel Coronavirus (SARS-CoV-2), outbreak that took place in Hubei (Wuhan, China) from December 2019 aroused numerous questions regarding the nature and the origin of the SARS-CoV-2. Literature review of the main publications from scientific data bases was undertaken. These data revealed similarities of symptoms and identity of genome with the SARS-CoV. In this review, the genetics and virulence factors of coronaviruses, the disease pathophysiology and epidemiology were examined.

Keywords: Pathophysiology, epidemiology, coronavirus diseases, genome, SARS-CoV, Togo, Germany

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How to Cite

Katawa, G., Gambogou, B., Nguepou, C. T., Ataba, E., Ritter, M., Kamassa, E. H., … Ameyapoh, Y. (2021). Human Coronaviruses: Genetics, Virulence Factors and Pathophysiology, Diseases’ Epidemiology. International Journal of Innovative Research in Medical Science, 6(10), 698–712. https://doi.org/10.23958/ijirms/vol06-i10/1232

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Copyright © 2021 Gnatoulma Katawa Banfitebiyi Gambogou Christèle T. Nguepou Essoham Ataba Manuel Ritter Eya H. Kamassa Fagdéba D. Bara Simplice D. Karou Yaovi Ameyapoh this is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This work is licensed under a Creative Commons Attribution 4.0 International License.