Systematic reviewOpen Access

Efficacy of Covid-19 Mitigation Strategies on Incidence

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DOI: 10.23958/ijirms/vol10-i05/2043· Pages: 191 - 200· Vol. 10, No. 05, (2025)· Published: May 12, 2025
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Abstract

This study aims at assessing the efficacy of COVID-19 mitigation strategies on incidence. It examines the efficacy of the test-trace-isolate-quarantine (TTIQ) strategy in the containment of COVID-19 pandemic to determine the role of the environment in the pandemic and to recommend appropriate practices in the management of COVID-19 outbreak in terms of contact tracing, screening, quarantine, and isolation. To achieve these objectives, the study uses the systematic literature review, whereby secondary data is utilised to address the problem. The study findings show that TTIQ is the best practice for application by medical healthcare practitioners to treat COVID-19 cases worldwide. The TTIQ approach positively impacts the efforts to contain the virus due to the structured measures and practices utilized in dealing with the pandemic. However, the specific characteristics of the environment such as the presence of the supporting healthcare practitioners, defined procedures for minimal interactions and the general application of the related best practices affect the outcome of the exercise and the effectiveness of the TTIQ. In the same way, the presence of qualified practitioners is critical in delivering the required guidelines and expected outcomes towards the containment of the virus. Consequently, the efforts to improve environmental characteristics significantly help in achieving the best outcomes in containing the virus by introducing the cases of infection and achieving high-quality care for infected patients. The need to embrace solutions that minimize the physical interactions and improve the efficacy of the strategies of the management of the pandemic necessitated the adoption of the digital solutions; which mainly consisted of the mobile app solutions and the website technologies to support the strategies implemented to the population.

Keywords

efficacycontact tracingscreeningquarantineisolationtest-trace-isolate-quarantine (TTIQ)COVID-19 pandemicand the environment

References

  1. Alimohamadi, Y., Sepandi, M., Taghdir, M. and Hosamirudsari, H., 2020. Determine the most common clinical symptoms in COVID-19 patients: a systematic review and meta-analysis. Journal of Preventive Medicine and Hygiene, 61(3), p.E304.Google Scholar ↗
  2. Andrews, P.L., Cai, W., Rudd, J.A. and Sanger, G.J., 2021. COVID‐19, nausea, and vomiting. Journal of Gastroenterology and Hepatology, 36(3), pp.646-656.Google Scholar ↗
  3. Ashcroft, P., Lehtinen, S. and Bonhoeffer, S., 2022. Test-trace-isolate-quarantine (TTIQ) intervention strategies after symptomatic COVID-19 case identification. PloS one, 17(2), p.e0263597.Google Scholar ↗
  4. Ayoubkhani, D. and Pawelek, P., 2021. Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 1 April 2021. Off Natl Stat, pp.1-16.Google Scholar ↗
  5. Bauchner, H. and Fontanarosa, P.B., 2020. Randomised clinical trials and COVID-19: managing expectations. JAMA, 323(22), pp.2262-2263.Google Scholar ↗
  6. Braun, V. and Clarke, V., 2019. Reflecting on reflexive thematic analysis. Qualitative Research in Sport, Exercise and Health, 11(4), pp.589-597.Google Scholar ↗
  7. Cao, X., 2020. COVID-19: immunopathology and its implications for therapy. Nature Reviews Immunology, 20(5), pp.269-270.Google Scholar ↗
  8. Carfì, A., Bernabei, R. and Landi, F., 2020. Persistent symptoms in patients after acute COVID-19. JAMA, 324(6), pp.603-605.Google Scholar ↗
  9. Ciotti, M., Ciccozzi, M., Terrinoni, A., Jiang, W.C., Wang, C.B. and Bernardini, S., 2020. The COVID-19 pandemic. Critical Reviews in Clinical Laboratory Sciences, 57(6), pp.365-388.Google Scholar ↗
  10. Clarke, V., Braun, V. and Hayfield, N., 2015. Thematic analysis. Qualitative psychology: A practical guide to research methods, 222(2015), p.248.Google Scholar ↗
  11. Conway, E., Walker, C., Baker, C., Lydeamore, M., Ryan, G.E., Campbell, T., Miller, J.C., Yeung, M., Kabashima, G., Wood, J. and Rebuli, N., 2022. COVID-19 vaccine coverage targets to inform reopening plans in a low incidence setting. medRxiv.Google Scholar ↗
  12. Cunningham, A.C., Goh, H.P. and Koh, D., 2020. Treatment of COVID-19: old tricks for new challenges. Critical Care, 24(1), pp.1-2.Google Scholar ↗
  13. Daniel, S.J., 2020. Education and the COVID-19 pandemic. Prospects, 49(1), pp.91-96.Google Scholar ↗
  14. Dowthwaite, L., Fischer, J., Vallejos, E.P., Portillo, V., Nichele, E., Goulden, M. and McAuley, D., 2021. Public adoption of and trust in the NHS COVID-19 contact tracing app in the United Kingdom: quantitative online survey study. Journal of Medical Internet Research, 23(9), p.e29085.Google Scholar ↗
  15. Elibol, E., 2021. Otolaryngological symptoms in COVID-19. European Archives of Oto-Rhino-Laryngology, 278(4), pp.1233-1236.Google Scholar ↗
  16. Eloranta, V. and Turunen, T., 2015. Seeking competitive advantage with service infusion: a systematic literature review. Journal of Service Management.Google Scholar ↗
  17. Fauci, A.S., Lane, H.C. and Redfield, R.R., 2020. COVID-19 navigating the uncharted. New England Journal of Medicine, 382(13), pp.1268-1269.Google Scholar ↗
  18. Feng, L.X., Jing, S.L., Hu, S.K., Wang, D.F. and Huo, H.F., 2020. Modelling the effects of media coverage and quarantine on the COVID-19 infections in the UK. Math Biosci Eng, 17(4), pp.3618-3636.Google Scholar ↗
  19. Gautier, J.F. and Ravussin, Y., 2020. A new symptom of COVID‐19: loss of taste and smell. Obesity, 28(5), pp.848-848.Google Scholar ↗
  20. Gilbody, S., Littlewood, E., McMillan, D., Chew-Graham, C.A., Bailey, D., Gascoyne, S., Sloan, C., Burke, L., Coventry, P., Crosland, S. and Fairhurst, C., 2021. Behavioural activation to prevent depression and loneliness among socially isolated older people with long-term conditions: the BASIL COVID-19 pilot randomised controlled trial. PLoS Medicine, 18(10), p.e1003779.Google Scholar ↗
  21. Gu, S., Ślusarczyk, B., Hajizada, S., Kovalyova, I. and Sakhbieva, A., 2021. Impact of the COVID-19 pandemic on online consumer purchasing behavior. Journal of Theoretical and Applied Electronic Commerce Research, 16(6), pp.2263-2281.Google Scholar ↗
  22. Hao, F., Tan, W., Jiang, L.I., Zhang, L., Zhao, X., Zou, Y., Hu, Y., Luo, X., Jiang, X., McIntyre, R.S. and Tran, B., 2020. Do psychiatric patients experience more psychiatric symptoms during COVID-19 pandemic and lockdown? A case-control study with service and research implications for immunopsychiatry. Brain, Behavior, and Immunity, 87, pp.100-106.Google Scholar ↗
  23. Hasan, N., Rana, R.U., Chowdhury, S., Dola, AJ and Rony, M.K.K., 2021. Ethical considerations in research. Journal of Nursing Research, Patient Safety and Practise (JNRPSP) 2799-1210, 1(01), pp.1-4.Google Scholar ↗
  24. Haynes, B.F., Corey, L., Fernandes, P., Gilbert, P.B., Hotez, P.J., Rao, S., Santos, M.R., Schuitemaker, H., Watson, M. and Arvin, A., 2020. Prospects for a safe COVID-19 vaccine. Science Translational Medicine, 12(568), p. eabe0948.Google Scholar ↗
  25. Iqbal, M.R. and Chaudhuri, A., 2020. COVID-19: Results of a national survey of United Kingdom healthcare professionals’ perceptions of current management strategy–A cross-sectional questionnaire study. International Journal of Surgery, 79, pp.156-161. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241367/Google Scholar ↗
  26. James, A., Plank, M.J., Hendy, S., Binny, R., Lustig, A., Steyn, N., et al., 2021. Successful contact tracing systems for COVID-19 rely on effective quarantine and isolation. PLoS ONE, 16(6), e0252499. https://doi.org/10.1371/journal.pone.0252499DOI ↗Google Scholar ↗
  27. Karabulut‐Ilgu, A., Jaramillo Cherrez, N. and Jahren, C.T., 2018. A systematic review of research on the flipped learning method in engineering education. British Journal of Educational Technology, 49(3), pp.398-411.Google Scholar ↗
  28. Lovato, A., de Filippis, C. and Marioni, G., 2020. Upper airway symptoms in coronavirus disease 2019 (COVID-19). American Journal of Otolaryngology.Google Scholar ↗
  29. Lythgoe, M.P. and Middleton, P., 2020. Ongoing clinical trials for the management of the COVID-19 pandemic. Trends in Pharmacological Sciences, 41(6), pp.363-382.Google Scholar ↗
  30. MacIntyre, C.R., 2020. Case isolation, contact tracing, and physical distancing are pillars of COVID-19 pandemic control, not optional choices. The Lancet Infectious Diseases, 20(10), pp.1105-1106.Google Scholar ↗
  31. Marini, J.J. and Gattinoni, L., 2020. Management of COVID-19 respiratory distress. JAMA, 323(22), pp.2329-2330.Google Scholar ↗
  32. Mathieu, E., Ritchie, H., Ortiz-Ospina, E., Roser, M., Hasell, J., Appel, C., Giattino, C. and Rodés-Guirao, L., 2021. A global database of COVID-19 vaccinations. Nature Human Behaviour, 5(7), pp.947-953.Google Scholar ↗
  33. May, C.R., Cummings, A., Myall, M., Harvey, J., Pope, C., Griffiths, P., Roderick, P., Arber, M., Boehmer, K., Mair, F.S. and Richardson, A., 2016. Experiences of long-term life-limiting conditions among patients and carers: what can we learn from a meta-review of systematic reviews of qualitative studies of chronic heart failure, chronic obstructive pulmonary disease and chronic kidney disease?. BMJ Open, 6(10), p.e011694.Google Scholar ↗
  34. Mbwogge, M., 2021. Mass testing with contact tracing compared to test and trace for the effective suppression of COVID-19 in the United Kingdom: systematic review. JMIRx med, 2(2), p.e27254.Google Scholar ↗
  35. McPherson, K.E., McAloney-Kocaman, K., McGlinchey, E., Faeth, P. and Armour, C., 2021. Longitudinal analysis of the UK COVID-19 psychological wellbeing study: trajectories of anxiety, depression and COVID-19-related stress symptomology. Psychiatry Research, 304, p.114138.Google Scholar ↗
  36. Nehme, M., Braillard, O., Alcoba, G., Aebischer Perone, S., Courvoisier, D., Chappuis, F., Guessous, I. and COVICARE TEAM†, 2021. COVID-19 symptoms: longitudinal evolution and persistence in outpatient settings. Annals of Internal Medicine, 174(5), pp.723-725.Google Scholar ↗
  37. Oh, J., Hwang, S., Long, K.Q., Kim, M., Park, K., Kwon, S.L., Artaza Barrios, O.E., Torres, I., Kavanagh, M., Kondo, N. and Kachur, S.P., 2021. Real world evidence of trace, test, isolation, and quarantine impact on the COVID-19 pandemic response performance.Google Scholar ↗
  38. Padidar, S., Liao, S.M., Magagula, S., Mahlaba, T.A.A., Nhlabatsi, N.M. and Lukas, S., 2021. Assessment of early COVID-19 compliance to and challenges with public health and social prevention measures in the Kingdom of Eswatini, using an online survey. Plos One, 16(6), p.e0253954.Google Scholar ↗
  39. Panovska-Griffiths, J., Kerr, C.C., Stuart, R.M., Mistry, D., Klein, D.J., Viner, R.M. and Bonell, C., 2020. Determining the optimal strategy for reopening schools, the impact of test and trace interventions, and the risk of occurrence of a second COVID-19 epidemic wave in the UK: a modelling study. The Lancet Child & Adolescent Health, 4(11), pp.817-827.Google Scholar ↗
  40. Paris Harper-Hardy, M.A., Ruebush, E., Allen, M., Carlin, M., Plescia, M. and Blumenstock, J.S., 2022. COVID-19 case investigation and contact tracing programs and practice: snapshots from the field.Google Scholar ↗
  41. Parra, A., Juanes, A., Losada, C.P., Álvarez-Sesmero, S., Santana, V.D., Martí, I., Urricelqui, J. and Rentero, D., 2020. Psychotic symptoms in COVID-19 patients. A retrospective descriptive study. Psychiatry Research, 291, p.113254.Google Scholar ↗
  42. Perez Vallejos, E., 2021. Public adoption of and trust in the NHS COVID-19 contact tracing app in the United Kingdom: Quantitative online survey study.Google Scholar ↗
  43. Quer, G., Radin, J.M., Gadaleta, M., Baca-Motes, K., Ariniello, L., Ramos, E., Kheterpal, V., Topol, E.J. and Steinhubl, S.R., 2021. Wearable sensor data and self-reported symptoms for COVID-19 detection. Nature Medicine, 27(1), pp.73-77.Google Scholar ↗
  44. Remington, R., 2020. Quality appraisal. In A Step-by-step guide to conducting an integrative review (pp. 45-55). Springer, Cham.Google Scholar ↗
  45. Rudroff, T., Fietsam, A.C., Deters, J.R., Bryant, A.D. and Kamholz, J., 2020. Post-COVID-19 fatigue: potential contributing factors. Brain Sciences, 10(12), p.1012.Google Scholar ↗
  46. Samuel, G. and Lucivero, F., 2021. Bringing ethics into governance: The case of the UK COVID-19 contact tracing app. International Journal of Health Governance.Google Scholar ↗
  47. Samuel, G., Roberts, S.L., Fiske, A., Lucivero, F., McLennan, S., Phillips, A., Hayes, S. and Johnson, S.B., 2022. COVID-19 contact tracing apps: UK public perceptions. Critical Public Health, 32(1), pp.31-43.Google Scholar ↗
  48. Savtale, S., Hippargekar, P., Bhise, S. and Kothule, S., 2022. Prevalence of otorhinolaryngological symptoms in COVID 19 patients. Indian Journal of Otolaryngology and Head & Neck Surgery, 74(2), pp.3378-3384.Google Scholar ↗
  49. Shi, Y., Wang, G., Cai, X.P., Deng, J.W., Zheng, L., Zhu, H.H., Zheng, M., Yang, B. and Chen, Z., 2020. An overview of COVID-19. Journal of Zhejiang University-SCIENCE B, 21(5), pp.343-360.Google Scholar ↗
  50. Smith, L.E., Potts, H.W., Amlôt, R., Fear, N.T., Michie, S. and Rubin, G.J., 2021. Adherence to the test, trace, and isolate system in the UK: results from 37 nationally representative surveys. BMJ, 372.Google Scholar ↗
  51. Stevanin, S., Palese, A., Bressan, V., Vehviläinen‐Julkunen, K. and Kvist, T., 2018. Workplace‐related generational characteristics of nurses: a mixed‐method systematic review. Journal of Advanced Nursing, 74(6), pp.1245-1263.Google Scholar ↗
  52. Wang, H.Y., Li, X.L., Yan, Z.R., Sun, X.P., Han, J. and Zhang, B.W., 2020. Potential neurological symptoms of COVID-19. Therapeutic Advances in Neurological Disorders, 13, p.1756286420917830.Google Scholar ↗
  53. Weng, L.M., Su, X. and Wang, X.Q., 2021. Pain symptoms in patients with coronavirus disease (COVID-19): a literature review. Journal of Pain Research, 14, p.147.Google Scholar ↗
  54. Williams, J.M., Randle, H. and Marlin, D., 2020. COVID-19: Impact on United Kingdom horse owners. Animals, 10(10), p.1862.Google Scholar ↗
  55. Williams, S.N., Armitage, C.J., Tampe, T. and Dienes, K., 2021. Public attitudes towards COVID‐19 contact tracing apps: a UK‐based focus group study. Health Expectations, 24(2), pp.377-385.Google Scholar ↗
  56. Yang, L., Liu, S., Liu, J., Zhang, Z., Wan, X., Huang, B., Chen, Y. and Zhang, Y., 2020. COVID-19: immunopathogenesis and Immunotherapeutics. Signal Transduction and Targeted Therapy, 5(1), pp.1-8.Google Scholar ↗
  57. Young, B.C., Eyre, D.W., Kendrick, S., White, C., Smith, S., Beveridge, G., Nonnenmacher, T., Ichofu, F., Hillier, J., Oakley, S. and Diamond, I., 2021. Daily testing for contacts of individuals with SARS-CoV-2 infection and attendance and SARS-CoV-2 transmission in English secondary schools and colleges: an open-label, cluster-randomised trial. The Lancet, 398(10307), pp.1217-1229.Google Scholar ↗
  58. Yuki, K., Fujiogi, M. and Koutsogiannaki, S., 2020. COVID-19 pathophysiology: a review. Clinical Immunology, 215, p.108427.Google Scholar ↗
  59. Zandi, G., Shahzad, I., Farrukh, M. and Kot, S., 2020. Supporting role of society and firms to COVID-19 management among medical practitioners. International Journal of Environmental Research and Public Health, 17(21), p.7961.Google Scholar ↗
  60. Zarei, M., Bose, D., Nouri‐Vaskeh, M., Tajiknia, V., Zand, R. and Ghasemi, M., 2022. Long‐term side effects and lingering symptoms post COVID‐19 recovery. Reviews in Medical Virology, 32(3), p.e2289.Google Scholar ↗
Author details
Jamil Aljehany
Department of Surgical Assistant, Office Manager to the Head of the MBBS Program, College of Medicine, Taibah University, Madinah, Saudi Arabia.
✉ Corresponding Author
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Sultan Alzarfani
Department of Laboratory Technician, Office Manager to the Dean and Supervisor of College Laboratories, College of Medicine, Taibah University, Madinah, Saudi Arabia.
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Mohammed Alharbi
Director of Administrative and Financial Affairs Department, College of Medicine, Taibah University, Madinah, Saudi Arabia.
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