Review Article | Open Access
Vol. 3 No. 11 (2018)
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Page No.: 2293 to 2300 |
https://doi.org/10.23958/ijirms/vol03-i11/467
Assistant professor, Department of Histopathology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Dr Debajyoti Chatterjee
Assistant professor, Department of Histopathology,
Room no 512, 5th floor, Department of Histopathology, Research block A, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Pin-160012.
Abstract
Gliomas are the commonest brain tumors, both in adults and children. In the past one decade there is a massive development in the understanding in the pathogenesis and genetics of glial tumors. With the incorporation of the molecular information, gliomas are now classified based both on their morphology and genetics. These changes have been adapted in the current (2016) world health organization (WHO) revised classification of tumors of central nervous system. Incorporation of the molecular information has helped in the accurate classification of glial tumors, which provides important prognostic and predictive information. In this review article, we shall have a brief look at the morphology of the glial tumors with their molecular pathology, in the light of the current literature.
Keywords:
Glioma, glioblastoma, diffuse midline glioma, isocitrate dehydrogenase, TERTpromoter
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Copyrights & License
Copyright © 2018 Dr Debajyoti Chatterjee this is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This work is licensed under a Creative Commons Attribution 4.0 International License.