Case ReportOpen Access

Paraneoplastic Dermatomyositis as the Initial Presentation of Endometrial Adenocarcinoma: First Reported Case in Latin America and Literature Review

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DOI: 10.23958/ijirms/vol10-i12/2146· Pages: 414 - 419· Vol. 10, No. 12, (2025)· Published: December 1, 2025
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Abstract

Idiopathic inflammatory myopathies are a group of rare autoimmune diseases. A subset of these cases may occur in association with an underlying malignancy, a condition known as cancer-associated myositis (CAM), reported in approximately 13% of cases according to the Euromyositis registry. The malignancies most commonly linked to this syndrome include cancers of the lung, thyroid, breast, stomach, ovaries, cervix, and hepatocellular carcinoma. However, the association with endometrial adenocarcinoma has been only rarely described in the medical literature. In our review, we identified six previously reported cases (from Japan, Canada, and the United States). We present the first documented case in Latin America of a patient who developed this uncommon form of CAM, characterized by severe clinical presentation and favorable response following treatment directed at the neoplasm and administration of intravenous immunoglobulin.

Keywords

LQASmethod CoverageChemopreventionSeasonalMalaria

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Author details
Carlos Andrés Berrocal Martínez
Internal Medicine Resident, Universidad del Valle, Cali, Colombia.
✉ Corresponding Author
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Valentina Torres Londoño
Internal Medicine, Universidad del Valle, Cali, Colombia.
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Lunevar Figueroa Torregroza
Internal Medicine and Rheumatology, Faculty Member – Universidad del Valle, Cali, Colombia.
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David Julian Del Castillo
Internal Medicine and Rheumatology, Faculty Member – Universidad del Valle, Cali, Colombia.
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Antonio María Zumaque Carrascal
Physician, Specialist in University Teaching, Master’s Degree in HIV, Universidad del Sinú, Montería, Colombia.
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Danna Vanessa Jiménez Gómez
General Practitioner, Universidad del Sinú, Montería, Colombia.
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