Abstract

Parathyroidectomy, of the 4 glands, with/without thyroidectomy is the most common cause of hypoparathyroidism. Autoimmunity is a rare etiology, either as an isolated endocrinopathy or as a component of autoimmune polyglandular syndrome 1 (APS 1). In this case report; we describe a patient with an adult-onset hypoparathyroidism and discuss its pathophysiology in relation to calcium-sensing receptors in addition to its diagnostic work up and management.

Keywords

  • Autoimmune
  • autoimmune polyglandular syndrome 1
  • calcium-sensing receptors
  • hypocalcemia
  • hypoparathyroidism
  • vitamin D
  • urolithiasis